Hydrocortisone Acetate 2.5% and Pramoxine HCl Cream 1%Hydrocortisone Acetate 2. 5% and Pramoxine HCl Cream 1% is a combination medication used to treat various skin conditions such as eczema, dermatitis, insect bites, and allergic reactions. Hydrocortisone acetate is a corticosteroid that helps reduce inflammation and irritation in the skin, while pramoxine HCl is a local anesthetic that helps relieve pain and itching. This cream is used topically and should only be applied to the affected area as