Pure Encapsulations SAMe (s-adenosylmethionine) 60CPure Encapsulations SAMe supports cognitive function, mood, liver health, and joint comfort. This naturally occurring compound participates in over 100 cellular reactions, promoting healthy methylation, neurotransmitter synthesis, and glutathione production. Clinical research demonstrates its effectiveness for mental clarity and joint flexibility. Formulated with hypoallergenic, vegan ingredients for optimal absorption and tolerability.