Natural Factors Melatonin 3mg 60'sMelatonin is the bodys own natural sleep hormone, which is produced in the brain in the pineal gland each evening when darkness falls. It is part of the biological clock that produces the circadian rhythm and prepares the body for sleep. But the natural rhythm of this clock can be disrupted, resulting in difficulty sleeping. How to use All uses except jet lag: At or before bedtime, 1 tablet once daily or as directed by a health care practitioner. Jet