Xgeva Denosumab Injection Vial 120 mg/1.7 mL (70 mg/mL) Single-Dose Vial by Amgen (RX) ** Requires RefrigerationXgeva is a prescription medication containing the active ingredient denosumab. It is supplied in a single dose vial, delivering 120 mg of denosumab in a 1. 7 mL solution (70 mg mL). Xgeva is manufactured and distributed by Amgen, a leader in biotechnology. Denosumab works by inhibiting the RANK ligand (RANKL), a protein essential for the formation, function, and survival of osteoclasts, the cells that break down bone. By inhibiting RANKL, Xgeva helps