Cosmedix Serum 16Stimulate and renew your skin to dramatically reduce the look of fine lines and wrinkles with microencapsulated Retinol Complex. Loaded with Vitamin E, this rapid renewal complex is the perfect way to introduce dry, sensitive skin to a Retinol product that traditionally cannot tolerate Retinol. How to use Apply a pea sized amount to clean skin as tolerated every 1 3 nights, working up to nightly use. May be followed with moisturiser if additional