Restylane Refyne with Lidocaine (1x1ml)How does Restylane Refyne work? Restylane Refyne contains the active ingredient ,non animal based Butanediol Diglycidyl Ether (BDDE). Optimal Balance Technology allows these dermal fillers to integrate smoothly into the skin, giving a higher acceptance rate by the patient's skin. OBT ensures an optimal balance between the level of cross linking and gel calibration that exists due to an equilibrium concentration of hyaluronic acid Individual's and