Depo Medrol for Injection 80 mg, 5 mL x 25/PackDepo Medrol 80 mg is an injectable corticosteroid. It is used to decrease inflammation caused by allergic, respiratory, skin, and eye reactions and certain conditions in the body. It is also helpful in treating endocrine, collagen diseases, and rheumatic disorders. Depo medrol 80 mg provides relief from various inflammation related conditions for patients. Pfizer Injectables Depo Medrol (methylprednisolone acetate) for Injection is a sterile injection