Pure B12 Folate Melt 90 lozengesCombination of vitamin B12 and folate as a lozenge Folate and vitamin B12 are close partners in metabolism. Together they can help reduce tiredness and fatigue. They also work as a team to break down homocysteine. Homocysteine is an amino acid that occurs in the body as an intermediate product and should be broken down quickly. With reduced intake (e. g. older people) or utilization, the vitamin B 12 and folic acid levels in the body can be reduced.