Sodium Bicarbonate 4.2% Injection Hospira, Single Dose 5 ml x 25/Tray (RX)Sodium Bicarbonate 4. 2% Injection Sodium bicarbonate 4. 2% injection is a sterile intravenous electrolyte solution used to treat metabolic acidosis and other conditions requiring systemic alkalinization. The 4. 2% solution contains a high concentration of sodium bicarbonate (about 42 mg mL, providing 0. 5 mEq each of Na and HCO per mL). This solution is hypertonic and has a near alkaline pH (~7. 08. 5). When given IV, it increases blood bicarbonate